京帮以北京为中心，同仁堂是其最著名的代表。传统工序可达二十余道，加工方法逾五十种。京帮重视选料、火候与成药规格的统一，形成了相对稳定的宫廷与市井双重传承。许多老药工的口述与师徒制仍是技艺延续的重要方式。
The Beijing school centres on the capital; Tongrentang is its best-known representative. Traditional processes can exceed twenty steps and fifty techniques. Emphasis falls on material selection, fire control and consistent finished standards, with both court and popular lineages. Oral transmission by master craftsmen remains an important channel of continuity.
樟帮源于江西樟树，是南方重要的药材集散与炮制中心之一。樟帮在切制、蒸煮、发酵等环节形成了鲜明的地方特色，工具与工序用语也与北方有所不同。樟树「药都」的历史地位，使该帮在长江以南影响深远。
The Zhang (Zhangshu) school originates in Zhangshu, Jiangxi, a major southern hub for materia medica trade and processing. It developed distinctive local styles in cutting, steaming, boiling and fermentation, with tools and terminology differing from northern practice. Zhangshu’s historical role as a “medicine capital” gave the school wide influence south of the Yangtze.