东汉末年 · 张仲景撰 · 约公元200年前后
Late Eastern Han · Compiled by Zhang Zhongjing · ca. 200 CE
据张仲景自序，因宗族多人死于伤寒，乃「勤求古训，博采众方」，撰成《伤寒杂病论》十六卷。原书不久散乱。西晋王叔和整理其中伤寒部分，编为《伤寒论》；杂病部分后来形成《金匮要略》。北宋治平二年（1065），校正医书局林亿、高保衡、孙奇等校定《伤寒论》，成为后世通行的「宋本」系统。明万历赵开美刻本是现存重要的宋本传本之一。
According to Zhang Zhongjing’s own preface, after many of his clansmen died of cold-damage disorders, he “diligently sought the teachings of the ancients and broadly collected formulas,” compiling the *Shanghan Zabing Lun* in sixteen juan. The original work soon became scattered. Wang Shuhe of the Western Jin rearranged the cold-damage portions into the *Shanghan Lun*; the miscellaneous-disease portions later formed the *Jingui Yaolue*. In 1065 the Song Bureau for the Correction of Medical Texts, under Lin Yi and colleagues, produced the standard “Song edition” of the *Shanghan Lun*. The Ming Wanli edition by Zhao Kaimei is one of the important surviving witnesses of that Song tradition.
以六经辨证为纲，把外感热病的演变与治疗原则系统化，并保存大量经方。它是中医辨证论治体系的重要奠基之作，也是后世方书与临床思维的重要源头。
Organised around the six-channel pattern differentiation, it systematises the progression and treatment of externally contracted febrile disease and preserves a large body of classical formulas. It is a foundational work for the pattern-differentiation-and-treatment system of Chinese medicine and a major source for later formula literature and clinical reasoning.